NICODOM Kidney Stone
Analysis Kit
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For Kidney
Stone Analysis by FTIR NICODOM Ltd. offers two different products: NICODOM IR Kidney Stones 1668
spectra – this is a spectral library
of Kidney Stones, compatible with most spectroscopic software packages and
operating systems. For description of the NICODOM
IR Kidney Stones 1668 spectra
click here. NICODOM Kidney Stone Analysis
Kit - combination of qualitative
and quantitative analysis, kidney stone guide, only compatible with Thermo
OMNIC SEARCH software (Nicolet FTIR spectrometers) The
„NICODOM Kidney Stones Analysis Kit“ software package has been created by
spectroscopists and medical doctors to allow semiautomated analysis of kidney
stones using Thermo (Nicolet) FTIR spectrometers with OMNIC software. This
software will not work without OMNIC software. OMNIC software can be
purchased thru the Thermo representative in you country, we cannot deliver
the OMNIC software. Technical
requirements. „NICODOM Kidney Stones Analysis Kit“ is an older software, last update was done 2006. This software
will only run with 32 bit operating systems. It has been tested with Win
10/32bit. It will not run with 64 bit systems. This software was optimized
for OMNIC 6. It still runs with OMNIC 9 but some settings must be done
manually and some features do not work properly. This software is NOT
compatible with OMNIC Paradigm. If you have OMNIC version higher than OMNIC
6.0 than please only order if you accept that this software was optimized for
OMNIC 6 and that for higher OMNIC versions we do not provide support. For newer
Thermo FTIR systems we strongly recommend to order NICODOM
IR Kidney Stones 1668 spectra
which is a spectral library of Kidney Stones, compatible with all OMNIC
versions and operating systems. The NICODOM Kidney Stone Analysis Kit consists of
three parts. NICODOM KIDNEY STONE LIBRARY - BASIC This approach is not new and allows analyzing
samples by less qualified personal. The library of about 800 spectra allows
analysis with +- 10% accuracy (error of 10-15 % is without clinical
relevance). This accuracy varies for different mixtures, best results (error
less than 5%) were reached for major components in concentration range of
30-70%. As far as no peak shifts were observed comparing spectra of pure
components with those of real mixtures, spectra of conceivable mixtures were
created by combination of pure components. On the other hand, pure kidney
stones must have been used, because their infrared spectra differ from those
of mineralogically or chemically pure substances. For example each real
urinary concrement contains a low content of unknown "matrix".
"Matrix" contains mostly organic components, that is why the SEARCH
operation in the region of 2900 - 3100 cm-1 can fail and thus searching in
finger print region is recommended. NICODOM KIDNEY STONE ANALYSIS A combination of qualitative and quantitative
analysis is used. The content of a component is calculated from the match
values of search result using a coded library of over 18.000 spectra and
special algorithms. This type of analysis rejects other than kidney stones
spectra, corrects or rejects distorted spectra and has improved accuracy.
Spectra of common artifacts, drug and rare stones are included. All results
include reliability factor of the analysis and can be stored with the
spectrum. Visual comparison of the sample spectrum with the theoretical
spectrum is also an important feature. 212 spectra files of real stones (found in human
kidney) and 23 spectra files of major pure components are also included as
examples to demonstrate capabilities of the software. Examples of result windows
(advanced analysis):
NICODOM KIDNEY STONE GUIDE This
part of the kit includes additional information about the kidney stones components.
Interpreted infrared spectra of stones and pure chemicals are included. Its
Raman spectrum, picture of the stone, other methods of chemical analysis
(qualitative, semiquantitative, quantitative), causes and occurrence of the
component, optical properties, table of peaks, structural formula and other
information is also included. This
guide also gives to the chemists a brief information about medical aspects of
kidney stone analysis, like diagnosis and therapy. You can choose what
information you want to display for the investigated stone (Whewellite as
example):
Each type of information
displays in a separate window
All information about one
stone displayed as "cascade" SAMPLING METHOD The spectra were collected and
software has been tested with KBr pellets transmission spectra. If your
sampling method is ATR or diffuse reflectance, the NICODOM Kidney Stone Analysis Kit will still deliver acceptable results
under following conditions: - Your spectra should be collected
with quality comparable to transmission spectra (noise, spectral range,
sample thickness, humidity…) - Your spectra should be
corrected (baseline correction, ATR
correction, Kubelka-Munk correction, those corrections are usually part of
your software) Please refer to ATR or diffuse
reflectance theory to understand limitations of those sampling methods. Note that today most laboratories use
ATR or diffuse reflectance sampling technique and they use NICODOM Kidney Stone Analysis Kit without problems. MORE INFORMATION For more information also view the
article as pdf file: http://www.ftir.cz/Kidclan2.pdf Download
promo material: http://www.ftir.cz/kid2sheet.pdf Download Kidney Stone Analysis Kit
Users Guide: http://www.ir-spectra.com/download/NICODOM_KS_Kit_Guide.pdf This software package requires Thermo (Nicolet)
OMNICTM software being installed on your computer. To download the list of spectra from this library,
to download a free demo library compatible with your software, to check the
format compatibility as well as for pricelist, ordering info and information
about all NICODOM IR/NIR Libraries and other NICODOM products please visit
our webpage.
NICODOM Kidney Stone
Analysis Kit Copyright © NICODOM 2006 -2020 NICODOM Ltd., Hlavni
2727, CZ-14100 Praha 4, Czech Republic, EU Tel: +420-281914970, Fax:
+420-281914971 |
